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知识就是力量；每天两篇推文，提供专业学术交流。
关键词：心血管科；最受关注论文；选刊；选题
做科研、尤其是选题，需要读很多文献；最高效的阅读方式是，先读领域内最受关注的论文。
我们通过大数据分析，找到了在过去一个月里发表的论文中，心血管科（"Cardiology"[Affiliation] OR "Cardiovascular"[Affiliation]）领域最受关注的论文；希望对同仁们快速了解本学科最新进展有帮助。
如果您需要这些论文的原文，请扫码文末的科研助手二维码。
A，心血管科研究
最受关注的论文

1，JACC本周综述：女性健康和心血管结果的社会经济决定因素

Socioeconomic Determinants of Health and Cardiovascular Outcomes in Women: JACC Review Topic of the Week. J Am Coll Cardiol. 2021 Nov 9;78(19):1919-1929. doi: 10.1016/j.jacc.2021.09.011.
获取全文请找科研助手，标注“20211204-1”。

2， T 细胞疗法相关的不良心、肺事件（使用FAERS 数据库）

Adverse Cardiovascular and Pulmonary Events Associated With Chimeric Antigen Receptor T-Cell Therapy. J Am Coll Cardiol. 2021 Nov 2;78(18):1800-1813. doi: 10.1016/j.jacc.2021.08.044.
获取全文请找科研助手，标注“20211204-2”。

3，血清载脂蛋白 A-I 耗竭是二氧化硅微粒诱导的心血管损伤的原因（小鼠实验）

Serum apolipoprotein A-I depletion is causative to silica nanoparticles-induced cardiovascular damage. Proc Natl Acad Sci U S A. 2021 Nov 2;118(44):e2108131118. doi: 10.1073/pnas.2108131118. 
获取全文请找科研助手，标注“20211204-3”。

4，房颤对外周动脉疾病结局的影响：对常规收集的初级保健数据的分析

THE IMPACT OF ATRIAL FIBRILLATION ON OUTCOMES OF PERIPHERAL ARTERIAL DISEASE: ANALYSIS OF ROUTINELY COLLECTED PRIMARY CARE DATA. Am J Med. 2021 Nov 15:S0002-9343(21)00733-6. doi: 10.1016/j.amjmed.2021.10.021. Epub ahead of print.

获取全文请找科研助手，标注“20211204-4”。
B，心血管科研究
最有影响力论文

5，外科主动脉瓣置换术后死亡原因（真实世界数据、队列研究）

Cause of Death After Surgical Aortic Valve Replacement: SWEDEHEART Observational Study. J Am Heart Assoc
. 2021 Nov 16;10(22):e022627. doi: 10.1161/JAHA.121.022627.

获取全文请找科研助手，标注“20211204-5”。
6，JAK-STAT通路：类风湿性关节炎心血管疾病和骨髓增生性肿瘤的新兴靶点
The JAK-STAT pathway: an emerging target for cardiovascular disease in rheumatoid arthritis and myeloproliferative neoplasms. Eur Heart J. 2021 Nov 7;42(42):4389-4400. doi: 10.1093/eurheartj/ehab447.
获取全文请找科研助手，标注“20211204-6”。

7，家族性高胆固醇血症：JACC研讨会焦点

Familial Hypercholesterolemia: JACC Focus Seminar 4/4. J Am Coll Cardiol. 2021 Nov 2;78(18):1831-1843. doi: 10.1016/j.jacc.2021.09.004.
获取全文请找科研助手，标注“20211204-7”。

8，24 小时尿钠钾排泄和心血管风险

24-Hour Urinary Sodium and Potassium Excretion and Cardiovascular Risk. N Engl J Med. 2021 Nov 13. doi: 10.1056/NEJMoa2109794. Epub ahead of print. 
获取全文请找科研助手，标注“20211204-8”。
C，投稿选刊
论文是知识的载体，也是成果的体现形式；投稿时选刊非常重要，可让你事半功倍。
在以("Cardiology"[Affiliation] OR "Cardiovascular"[Affiliation]) AND 2021/10/20:2021/11/20[Date - Publication]为检索词的情况下，过去的1个月里，心血管科领域共发表了7,453篇Medline收录的论文，我们对这些论文进行了大数据分析。
发表心血管科论文最多的期刊依次为：Catheter Cardiovasc Interv(IF 2.7), Front Cardiovasc Med (IF 6.1), Int J Cardiol (IF 4.2),J Clin Med(IF 4.2), J Am Heart Assoc (IF 5.5)等。
(最近1个月，发表心血管科论文最多的期刊)
我们也附上这些期刊的分区、平均接受周期等参数。供您投稿时参考。

D，选题借鉴
除了上述最值得借鉴的论文之外，我们每一期都努力找到值得医生/研究生学习的研究者，期望其发表的论文对您的选题有启发。
本期我们推荐的是复旦大学中山医院的Ge,Junbo，Dr. Ge不但擅长冠脉病变、心律失常等心内科疾病的临床研究，也很善于结合热门靶点深挖机制，尤其是预测模型研究和预后研究，都是临床常见研究类型，非常值得借鉴学习。↓↓↓
1.(2021) A Simple Model to Predict
Repeat Revascularization After Drug-Eluting Stent Implantation in Patients With Stable Coronary Artery Disease
Angiology
2.(2021)
Outcomes
of contemporary versus conventional reverse controlled and antegrade and retrograde subintimal tracking in chronic total occlusion revascularization
Catheter Cardiovasc Interv
3.(2021) Intravenous Nicorandil During Primary Percutaneous Coronary intervention in Patients with ST-Elevation Myocardial Infarction:
Rationale and Design
of the CLinical Efficacy and sAfety of intravenous Nicorandil (CLEAN) trial
Am Heart J
4.(2021) A
Predictive Model
Based on a New CI-AKI Definition to Predict Contrast Induced Nephropathy in Patients With Coronary Artery Disease With Relatively Normal Renal Function
Front Cardiovasc Med
5.(2021) m6A demethylase FTO attenuates cardiac dysfunction by regulating glucose uptake and glycolysis in mice with pressure overload-induced heart failure
Signal Transduct Target Ther
6.(2021) Cardiac resynchronization therapy via left bundle branch pacing vs. optimized biventricular pacing with adaptive algorithm in heart failure with left bundle branch block: a prospective, multi-centre, observational study
Europace
7.(2021) AT1 receptor blocker inhibits HMGB1 expression in pressure overload-induced acute cardiac dysfunction by suppressing the MAPK/NF-κB signaling pathway
Clin Exp Hypertens
8.(2021) Interleukin-18 accelerates cardiac inflammation and dysfunction during ischemia/reperfusion injury by transcriptional activation of CXCL16
Cell Signal
9.(2021) Real-time echocardiographic guidance for transcatheter repair noncentral mitral regurgitation using the novel Valve Clamp system
J Card Surg
10.(2021) The critical roles of m6A modification in metabolic abnormality and cardiovascular diseases
Genes Dis
另外，哈佛大学Brigham and Women's Hospital 的 Bhatt, Deepak L 除了擅长多疾病交叉的临床研究外，同样懂得如何将热门靶点应用于心内科临床研究，特别是预防、危险因素等研究思路设计很值得一看。  ↓↓↓
1.(2021) Recruitment Practices in Multicenter Randomized Clinical Trials: Time for a Relook
J Am Heart Assoc
2.(2021) Women and Diabetes:
Preventing
Heart Disease in a New Era of Therapies
Eur Cardiol
3.(2021) Dual pathway inhibition in atherothrombosis
prevention
: yes, now we can!
Minerva Cardiol Angiol
4.(2021) The
reduction in cardiovascular risk
in REDUCE-IT is due to eicosapentaenoic acid in icosapent ethyl
Eur Heart J
5.(2021) Addressing Imaging Pitfalls to
Reduce
Cardiovascular Disease Misdiagnosis in Patients With Breast Cancer Following Reconstruction
JAMA Cardiol
6.(2021) SGLT-2 inhibitors in heart failure: Time for broader eligibility and earlier initiation
Cleve Clin J Med
7.(2021) Innovation in intervention
Prog Cardiovasc Dis
8.(2021) Serum Potassium and Mortality in High-
Risk
Patients: SPRINT
Hypertension
9.(2021)
Improving Communication of Incidental Imaging Findings: Transforming Uncertainty Into Opportunity
Mayo Clin Proc

也期待您能够受到一些启发，找到更好的临床科研方向；研究顺利发表，解决更多临床问题。
更多SCI论文和基金模板，在本公众号主页面下回复“临床科研”、“模板”或“基金”均可以获得对应资料。并支持按照科室搜索，如回复“心血管科”，即获得该专题的资料。
编辑：Henry，微信号：Healsan。
文中插图多为原文截图，版权均归原作者及出版社所有；仅供学习用。
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