当地时间9日,美国公共卫生新闻网站STAT报道称,因怀疑一名疫苗受试者出现严重不良反应,英国一支备受瞩目的新冠疫苗暂停了三期临床试验。
据悉,这支疫苗受到美国政府资助,由牛津大学与英国制药巨头阿斯利康联合研发。
A large, Phase 3 study testing a Covid-19 vaccine being developed by AstraZeneca and the University of Oxford…has been put on hold due to a suspected serious adverse reaction in a participant in the United Kingdom.
STAT报道截图
疫苗研发按下“暂停键”
阿斯利康表示:常规操作

阿斯利康在一则声明中称,该公司已启动标准审核流程,暂停了疫苗接种,以允许审查安全数据。此外,该公司将搁置研究进程。
A spokesperson for AstraZeneca…said in a statement that the company's "standard review process triggered a pause to vaccination to allow review of safety data." AstraZeneca said it initiated the study hold.
一位知情人士透露,受试者预期会康复,但不良反应的性质和发生的时间尚不清楚。
The nature of the adverse reaction and when it happened were not immediately known, though the participant is expected to recover, according to an individual familiar with the matter. 
阿斯利康发言人表示,暂停试验并启动审查程序属于“常规操作”
在一项试验中,只要其中一项试验存在可能无法解释的病症,就必须采取常规行动,从而确保试验的完整性。
The spokesperson described the pause as "a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials."
视频:中国日报记者杨易林
阿斯利康发言人称,公司正努力加快对此事的核查,以最大程度地减小该事件对疫苗试验时间的影响。
The spokesperson also said that the company is "working to expedite the review of the single event to minimize any potential impact on the trial timeline."
据称这是该疫苗临床试验中第二次有受试者出现病症反应。
STAT报道称,目前全球有9支候选疫苗进入三期试验阶段,阿斯利康研发的疫苗是目前已知的首支暂停临床试验的疫苗。
There are currently nine vaccine candidates in Phase 3 trials. AstraZeneca's is the first Phase 3 Covid-19 vaccine trial known to have been put on hold.
特朗普曾对该疫苗寄予厚望
希望大选前能用上
据美国政治新闻网(Politico)报道,阿斯利康疫苗是特朗普“弯道超车计划”(Operation Warp Speed)所支持的几种疫苗之一,旨在加速新冠疫苗研发。
The AstraZeneca vaccine, which the company is developing with scientists at Oxford University, is one of several backed by the U.S. government's Operation Warp Speed vaccine accelerator. 
Politico报道截图
特朗普政府已同意向阿斯利康疫苗项目资助12亿美元,并提前预定了3亿剂疫苗。
The US government has agreed to pay up to $1.2 billion to aid the development and manufacturing of the vaccine, and to secure 300 million doses.
此前,美国消费者新闻与商业频道(CNBC)在一篇报道中称,特朗普政府曾考虑在大选日之前,对阿斯利康这支疫苗进行紧急使用授权,以便能够在美国使用。
The Trump administration is considering fast tracking an experimental coronavirus vaccine developed in the UK for use in the United States ahead of the nation’s upcoming presidential election.
CNBC报道截图
报道称,大选前若能使用该疫苗,则足以证明已面临广泛质疑的特朗普政府,具备应对新冠疫情的能力。
The availability of a vaccine before the US presidential election could allow Trump to justify his administration's handling of the coronavirus pandemic, which has faced widespread criticism. 
据悉,阿斯利康疫苗的三期临床试验,同时在美国、英国、巴西和南非进行,以确定疫苗的安全性和有效性。

AstraZeneca is running phase three trials in the US, UK, Brazil and South Africa to determine whether the vaccine is safe and effective. 
目前,随着独立委员会启动对该公司疫苗安全性的核查,这些研究均被暂停。
Those studies are now on hold while the company investigates the potential safety issue.
编辑:胡雨濛
中国日报(ID:chinadailywx)综合STAT、CNBC、Politico报道
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