「简报」新研究通过人造大脑确定了创伤性脑损伤的遗传影响;科学家在联合国塑料和化学品会谈之前指出利益冲突
在过去的十年中,随着医生试图了解其在慢性创伤性脑病(CTE)等神经系统疾病中的作用,创伤性脑损伤(TBI)的严重性得到了强调。CTE 是一种由反复头部损伤引起的进行性致命性脑部疾病,因为反复发作而臭名昭著。包括 Mike Webster 和 Aaron Hernandez 在内的 NFL 职业球员都曾得过。
为了在不使用小鼠、灵长类动物或死后人体组织的情况下更好地了解人类 TBI,卡耐基梅隆大学和匹兹堡大学医学中心的研究人员在人类大脑类器官上重现了轻度和中度 TBI,以分析它对大脑的影响。结果令人震惊。利用 RNA 测序(一种用于发现细胞中哪些基因被打开或关闭的方法),研究人员确定了导致 TBI 并发症的前三重要的基因。
了解更多:
https://engineering.cmu.edu/news-events/news/2023/11/17-tackling-concussions.html
The severity of traumatic brain injury (TBI) has been underscored in the last decade as doctors seek to understand its role in neurological diseases like chronic traumatic encephalopathy (CTE), a progressive and fatal brain disorder caused by repeated head injury that gained notoriety for its markedness among NFL pros including Mike Webster and Aaron Hernandez.
To better understand TBI in humans without the use of mice, primates, or postmortem human tissue, researchers at Carnegie Mellon University and the University of Pittsburgh Medical Center recreated mild and moderate TBI on human cerebral organoids to analyze TBI effects on the brain. The results were astounding. Using RNA sequencing, a method used to discover which genes are turned on or off in cells, the researchers identified the top three genes responsible for TBI complications
Learn More:
https://engineering.cmu.edu/news-events/news/2023/11/17-tackling-concussions.html
一个由 35 名科学家组成的国际团体呼吁,利益冲突困扰着全球塑料条约的谈判,也妨碍了在其他健康和环境问题上采取及时行动。他们敦促实施严格的指导方针,以防止同样的问题影响联合国即将成立的化学品科学政策小组。
呼吁变革的科学家之一是来自卡耐基梅隆大学的 Ryan Sullivan,他刚刚在“不断变化的星球上的环境系统”课堂中涵盖了环境健康和有毒物质的内容。
了解更多:
https://www.cmu.edu/mcs/news-events/2023/1113_scientists-flag-conflict-interest.html
An international group of 35 scientists is calling out conflicts of interest plaguing global plastic treaty negotiations and that have interfered with timely action on other health and environmental issues. They urge the implementation of strict guidelines to prevent the same problems from affecting the UN's upcoming Science Policy Panel on chemicals.
Among the scientists calling for change is Carnegie Mellon University's Ryan Sullivan, who just covered environmental health and toxic substances in his course Environmental Systems on a Changing Planet.
Learn More:
https://www.cmu.edu/mcs/news-events/2023/1113_scientists-flag-conflict-interest.html
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